Has anyone encountered this situation? An error was reported when viewing the results, and the highest score was -706 and -641. How to fix it? Thanks a lot.
There is most likely something wrong with the docking - such affinities are way outside any reasonable expected value.
I would have a look at the structure of your ligands (and receptor), perhaps something is wrong there. Loading these (and your receptor structure) in Pymol, for example, might give you some valuable insight.
Thanks for your suggestions. I have fixed it through autodocking it again. The ligand and receptor seems reasonable in Pymol.